Open AccessThe Effects of Vasoconstriction And Volume Expansion on Veno-Arterial ECMO Flow
Author(s) -
Per Werner Möller,
Anisa Hana,
Paul Philipp Heinisch,
Shengchen Liu,
Siamak Djafarzadeh,
Matthias Hænggi,
Andreas Bloch,
Jukka Takala,
Stephan M. Jakob,
David Berger
Publication year - 2019
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000001197
Subject(s) - venous return curve , vasoconstriction , medicine , mean circulatory filling pressure , cardiology , extracorporeal membrane oxygenation , anesthesia , central venous pressure , vascular resistance , afterload , blood volume , hemodynamics , blood pressure , heart rate
Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is gaining widespread use in the treatment of severe cardiorespiratory failure. Blood volume expansion is commonly used to increase ECMO flow (QECMO), with risk of positive fluid balance and worsening prognosis. We studied the effects of vasoconstriction on recruitment of blood volume as an alternative for increasing QECMO, based on the concepts of venous return.