Open AccessTEG Lysis Shutdown Represents Coagulopathy in Bleeding Trauma Patients: Analysis of the PROPPR Cohort
Author(s) -
Jessica C. Cardenas,
Charles E. Wade,
Bryan A. Cotton,
Mitchell J. George,
John B. Holcomb,
Martin A. Schreiber,
Nathan J. White
Publication year - 2019
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000001160
Subject(s) - fibrinolysis , medicine , fibrinogen , thrombelastography , coagulopathy , hyperfibrinolysis , shutdown , platelet , gastroenterology , nuclear engineering , engineering
Thrombelastography (TEG) fibrinolysis shutdown after trauma is associated with increased mortality due to hypercoagulability-associated organ failure. However, a lack of mechanistic data has precluded the development of novel interventions to treat shutdown.