Open AccessMetabolomic Profile of ARDS by Nuclear Magnetic Resonance Spectroscopy in Patients With H1N1 Influenza Virus Pneumonia
Author(s) -
José Luis Izquierdo-García,
Nicolás Nin,
Jorge Jimenez-Clemente,
Juan Pablo Horcajada,
Mar Arenas-Miras,
Joaquim Gea,
Andrés Esteban,
Jesús Ruíz-Cabello,
José A. Lorente
Publication year - 2018
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000001099
Subject(s) - ards , pneumonia , metabolomics , viral pneumonia , medicine , influenza a virus , glutamine , gastroenterology , lung , virus , immunology , biology , disease , bioinformatics , amino acid , biochemistry , covid-19 , infectious disease (medical specialty)
The integrated analysis of changes in the metabolic profile could be critical for the discovery of biomarkers of lung injury, and also for generating new pathophysiological hypotheses and designing novel therapeutic targets for the acute respiratory distress syndrome (ARDS). This study aimed at developing a nuclear magnetic resonance (NMR)-based approach for the identification of the metabolomic profile of ARDS in patients with H1N1 influenza virus pneumonia.