Open AccessA Novel Perfusion System for Damage Control of Hyperkalemia in Swine
Author(s) -
Guillaume L. Hoareau,
Harris W. Kashtan,
Lauren Walker,
Carl A. Beyer,
Andrew Wishy,
J. Grayson,
James D. Ross,
Ian J. Stewart
Publication year - 2018
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000001079
Subject(s) - hyperkalemia , hemoperfusion , medicine , dialysis , anesthesia , potassium , perfusion , extracorporeal , renal replacement therapy , hemodialysis , refractory (planetary science) , resuscitation , catheter , thrombosis , urology , surgery , chemistry , physics , organic chemistry , astrobiology
The standard of care for refractory hyperkalemia is renal replacement therapy (RRT). However, traditional RRT requires specialized equipment, trained personnel, and large amounts of dialysate. It is therefore poorly suited for austere environments. We hypothesized that a simplified hemoperfusion system could control serum potassium concentration in a swine model of acute hyperkalemia.