Open AccessProcalcitonin and MR-Proadrenomedullin Combination with SOFA and qSOFA Scores for Sepsis Diagnosis and Prognosis: A Diagnostic Algorithm
Author(s) -
Silvia Spoto,
Eleonora Cella,
Marina De Cesaris,
Luciana Locorriere,
Silvia Mazzaroppi,
Edoardo Nobile,
Arcangela Michela Lanotte,
Lucia Pedicino,
Marta Fogolari,
Sebastiano Costantino,
Giordano Dicuonzo,
Massimo Ciccozzi,
Silvia Angeletti
Publication year - 2018
Publication title -
shock
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.095
H-Index - 117
eISSN - 1540-0514
pISSN - 1073-2322
DOI - 10.1097/shk.0000000000001023
Subject(s) - procalcitonin , septic shock , sepsis , medicine , receiver operating characteristic , sofa score , organ dysfunction , algorithm , gastroenterology , computer science
The third Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) defined sepsis as an organ dysfunction consequent to infection. A Sequential Organ Failure Assessment (SOFA) score at least 2 identifies sepsis. In this study, procalcitonin (PCT) and midregional pro-adrenomedullin (MR-proADM) were evaluated along with SOFA and quick SOFA (qSOFA) scores in patients with sepsis or septic shock.