
Quantification of Perinodular Emphysema in High-risk Patients Offers No Benefit in Lung Nodule Risk-Stratification of Malignancy Potential
Author(s) -
William H. Amundson,
Eric J. Swanson,
Ashley Petersen,
Brian Bell,
Charles R. Hatt,
Chris H. Wendt
Publication year - 2019
Publication title -
journal of thoracic imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.836
H-Index - 57
eISSN - 1536-0237
pISSN - 0883-5993
DOI - 10.1097/rti.0000000000000465
Subject(s) - medicine , hounsfield scale , lung cancer , nodule (geology) , lung , lung cancer screening , radiology , malignancy , nuclear medicine , pathology , computed tomography , paleontology , biology
Pulmonary nodules, found either incidentally or on lung cancer screening, are common. Evaluating the benign or malignant nature of these nodules is costly in terms of patient risk and expense. The presence of both global and regional emphysema has been linked to increased lung cancer risk. We sought to determine whether the measurement of emphysema directly adjacent to a lung nodule could inform the likelihood of a nodule being malignant.