Open AccessReview of Magnetic Resonance Spectroscopy in the Liver and the Pancreas
Author(s) -
William H. Perman,
N Balci,
Isin Akduman
Publication year - 2009
Publication title -
topics in magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.547
H-Index - 53
eISSN - 1536-1004
pISSN - 0899-3459
DOI - 10.1097/rmr.0b013e3181c422f1
Subject(s) - nuclear magnetic resonance , proton magnetic resonance , magnetic resonance imaging , nuclear magnetic resonance spectroscopy , spectroscopy , voxel , in vivo magnetic resonance spectroscopy , pancreas , chemistry , magnetic resonance spectroscopic imaging , abdomen , in vivo , volume (thermodynamics) , radiology , medicine , biochemistry , biology , physics , microbiology and biotechnology , quantum mechanics
Proton magnetic resonance spectroscopy is a powerful tool for in vivo biochemical characterization of normal and abnormal tissues. The initial application in the abdomen was the measurement of fat concentration in the liver using chemical shift imaging. The success of chemical shift imaging in providing a semiquantitative measure of liver fat concentration led to the application of the more quantitative single-voxel volume-selective spectroscopy of the liver. This single-voxel volume-selective spectroscopic technique is able to characterize the different lipids and metabolites present in the liver and the pancreas, providing information about the ratio of unsaturated and saturated lipids. The purposes of this article were to review the spectroscopic techniques and to discuss some of the clinical applications of these techniques in the abdomen.