Open AccessEvaluation of the Hybrid Tracer Indocyanine Green–99mTc-Nanocolloid for Sentinel Node Biopsy in Bladder Cancer—A Prospective Pilot Study
Author(s) -
Daphne D. D. Rietbergen,
Erik J. van Gennep,
G.H. KleinJan,
Maarten L. Donswijk,
Renato A. Valdés Olmos,
Bas W. van Rhijn,
Henk G. van der Poel,
F.W.B. van Leeuwen
Publication year - 2022
Publication title -
clinical nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.637
H-Index - 57
eISSN - 1536-0229
pISSN - 0363-9762
DOI - 10.1097/rlu.0000000000004301
Subject(s) - medicine , cystectomy , bladder cancer , indocyanine green , lymph node , biopsy , sentinel node , sentinel lymph node , radiology , histopathology , dissection (medical) , cancer , urology , surgery , pathology , breast cancer
In muscle-invasive bladder cancer (MIBC), lymph node invasion has proven to be an independent predictor of disease recurrence and cancer-specific survival. We evaluated the feasibility of targeting the sentinel node (SN) for biopsy in MIBC patients using the hybrid tracer indocyanine green (ICG)- 99m Tc-nanocolloid for simultaneous radioguidance and fluorescence guidance.