Open AccessDetecting Interval Distant Metastases With 18F-FDG PET/CT After Neoadjuvant Chemoradiotherapy for Locally Advanced Esophageal Cancer
Author(s) -
Tiuri E. Kroese,
Jelle P. Ruurda,
Anne S Bakker,
Jasvir Jairam,
Stella Mook,
Sylvia van der Horst,
Gert J. Meijer,
Nadia Haj Mohammad,
Peter S.N. van Rossum,
Richard van Hillegersberg
Publication year - 2022
Publication title -
clinical nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.637
H-Index - 57
eISSN - 1536-0229
pISSN - 0363-9762
DOI - 10.1097/rlu.0000000000004191
Subject(s) - medicine , esophageal cancer , stage (stratigraphy) , esophagectomy , confidence interval , radiology , chemoradiotherapy , retrospective cohort study , cancer , incidence (geometry) , oncology , physics , paleontology , optics , biology
Patients with esophageal cancer can develop distant metastases between the start of neoadjuvant chemoradiotherapy (nCRT) and planned surgery (ie, interval distant metastases). 18F-FDG PET/CT restaging after nCRT detects interval distant metastases in ~8% of patients. This study aimed to identify patients for whom 18F-FDG PET/CT restaging after nCRT could be omitted using an existing prediction model predicting for interval distant metastases or by using clinical stage groups.