Open Access18F-FBPA PET in Sarcoidosis
Author(s) -
Tadashi Watabe,
Hiroaki Shiba,
Sadahiro Naka,
Takashi Kamiya,
Shumei Murakami
Publication year - 2020
Publication title -
clinical nuclear medicine
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 0.637
H-Index - 57
eISSN - 1536-0229
pISSN - 0363-9762
DOI - 10.1097/rlu.0000000000003274
Subject(s) - medicine , lymph , sarcoidosis , pet ct , nuclear medicine , inflammation , melanoma , positron emission tomography , pathology , cancer research
A 68-year-old man with sarcoidosis showed high F-FDG uptake in the mediastinal and hilar lymph nodes on F-FDG PET, suggesting active inflammation. F-fluoro-boronophenylalanine (FBPA) PET showed no significant uptake in the mediastinal and hilar lymph nodes, suggesting its cancer specificity as a substrate of L-type amino acid transporter 1. F-fluoro-boronophenylalanine PET can be used for precise evaluation in oncology when the differentiation between inflammation and metastasis is inconclusive on F-FDG PET.