Open AccessPattern of FDG and MET Distribution in High- and Low-Grade Gliomas on PET Images
Author(s) -
Miwako Takahashi,
Tsutomu Sawada,
Akitake Mukasa,
Shota Tanaka,
Shunsuke Yanagisawa,
Toshimitsu Momose
Publication year - 2019
Publication title -
clinical nuclear medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.637
H-Index - 57
eISSN - 1536-0229
pISSN - 0363-9762
DOI - 10.1097/rlu.0000000000002460
Subject(s) - medicine , nuclear medicine , glioma , cutoff , positron emission tomography , standardized uptake value , radiology , cancer research , quantum mechanics , physics
This study aimed to determine the most effective metabolic index of FDG-PET and MET-PET to differentiate high- and low-grade gliomas, and then to characterize tumor metabolism according to the 2016 WHO classification. We also developed a new calculation method of potential infiltrative tumor volume to overcome the current limitations of tumor evaluation according to metabolic index, which focuses solely on tumor core area.