Open AccessMagnetization Transfer Imaging Predicts Porcine Kidney Recovery After Revascularization of Renal Artery Stenosis
Author(s) -
Mohsen Afarideh,
Kai Jiang,
Christopher M. Ferguson,
John R. Woollard,
James F. Glockner,
Lilach O. Lerman
Publication year - 2020
Publication title -
investigative radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.33
H-Index - 114
eISSN - 1536-0210
pISSN - 0020-9996
DOI - 10.1097/rli.0000000000000711
Subject(s) - renal artery stenosis , kidney , renovascular hypertension , renal function , medicine , renal blood flow , kidney disease , perfusion , renal artery , cardiology , renal artery obstruction , hemodynamics , radiology
Stenotic kidney (STK) and contralateral kidney magnetization transfer ratios (MTRs; Mt/M0) were measured at 3.0-T magnetic resonance imaging, at offset frequencies of 600 and 1000 Hz, before and 1 month post-PTRA in 7 RVD pigs. Stenotic kidney MTR was correlated to renal perfusion, renal blood flow (RBF), and glomerular filtration rate (GFR), determined using multidetector computed tomography and with ex vivo renal fibrosis (trichrome staining). Untreated RVD (n = 6) and normal pigs (n = 7) served as controls.