Open AccessPhysicochemical and Pharmacokinetic Profiles of Gadopiclenol
Author(s) -
Caroline Robic,
Marc Port,
Olivier Rousseaux,
Stéphanie Louguet,
Nathalie Fretellier,
Sarah Catoen,
Cécile Factor,
Soizic Le Greneur,
Christelle Medina,
Philippe Bourrinet,
Isabelle Raynal,
JeanMarc Idée,
Claire Corot
Publication year - 2019
Publication title -
investigative radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.33
H-Index - 114
eISSN - 1536-0210
pISSN - 0020-9996
DOI - 10.1097/rli.0000000000000563
Subject(s) - gadodiamide , gadolinium , chemistry , relaxometry , pharmacokinetics , dissociation constant , gadobutrol , nuclear magnetic resonance , nuclear chemistry , magnetic resonance imaging , medicine , biochemistry , physics , receptor , organic chemistry , spin echo , radiology
We aimed to evaluate gadopiclenol, a newly developed extracellular nonspecific macrocyclic gadolinium-based contrast agent (GBCA) having high relaxivity properties, which was designed to increase lesion detection and characterization by magnetic resonance imaging.