Open AccessAssessment of Pharmacokinetic, Pharmacodynamic Profile, and Tolerance of Gadopiclenol, A New High Relaxivity GBCA, in Healthy Subjects and Patients With Brain Lesions (Phase I/IIa Study)
Author(s) -
Jing Hao,
Philippe Bourrinet,
P. Desché
Publication year - 2019
Publication title -
investigative radiology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.33
H-Index - 114
eISSN - 1536-0210
pISSN - 0020-9996
DOI - 10.1097/rli.0000000000000556
Subject(s) - pharmacokinetics , pharmacodynamics , medicine , placebo , urine , nuclear medicine , magnetic resonance imaging , phases of clinical research , area under the curve , urology , pharmacology , pathology , clinical trial , radiology , alternative medicine
The aim of this study was to evaluate the pharmacokinetics, safety profile, and pharmacodynamics of gadopiclenol, a new high relaxivity macrocyclic gadolinium-based contrast agent, in healthy subjects and patients with brain lesions.