Open AccessNew management approaches to tuberculosis in people living with HIV
Author(s) -
David V. Mhango,
David Mzinza,
Kondwani Jambo,
Henry C. Mwandumba
Publication year - 2021
Publication title -
current opinion in infectious diseases/current opinion in infectious diseases, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.68
H-Index - 103
eISSN - 1080-7861
pISSN - 0951-7375
DOI - 10.1097/qco.0000000000000704
Subject(s) - medicine , dolutegravir , tuberculosis , intensive care medicine , human immunodeficiency virus (hiv) , integrase , adverse effect , optimism , mycobacterium tuberculosis , drug , antiretroviral therapy , immunology , viral load , pharmacology , pathology , psychology , social psychology
People living with HIV (PLWH) are commonly coinfected with Mycobacterium tuberculosis, particularly in high-transmission resource-limited regions. Despite expanded access to antiretroviral therapy and tuberculosis (TB) treatment, TB remains the leading cause of death among PLWH. This review discusses recent advances in the management of TB in PLWH and examines emerging therapeutic approaches to improve outcomes of HIV-associated TB.