Open AccessUpdate on group A streptococcal vaccine development
Author(s) -
James B. Dale,
Mark J. Walker
Publication year - 2020
Publication title -
current opinion in infectious diseases/current opinion in infectious diseases, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.68
H-Index - 103
eISSN - 1080-7861
pISSN - 0951-7375
DOI - 10.1097/qco.0000000000000644
Subject(s) - medicine , immunogenicity , immunology , antigen , clinical trial
There is a global need for well tolerated, effective, and affordable vaccines to prevent group A streptococcal infections and their most serious complications. The aim of this review is to highlight the recent progress in the identification of promising vaccine antigens and new approaches to vaccine design that address the complexities of group A streptococcal pathogenesis and epidemiology.