Open AccessAntibiotic de-escalation in the ICU
Author(s) -
José GarnachoMontero,
Ana EscorescaOrtega,
Esperanza Fernández-Delgado
Publication year - 2015
Publication title -
current opinion in infectious diseases/current opinion in infectious diseases, with evaluated medline
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.68
H-Index - 103
eISSN - 1080-7861
pISSN - 0951-7375
DOI - 10.1097/qco.0000000000000141
Subject(s) - de escalation , medicine , ventilator associated pneumonia , intensive care medicine , discontinuation , pneumonia , antibiotics , observational study , sepsis , broad spectrum , intensive care unit , critically ill , chemistry , microbiology and biotechnology , combinatorial chemistry , biology
An antimicrobial policy consisting of the initial use of wide-spectrum antimicrobials followed by a reassessment of treatment when culture results are available is termed de-escalation therapy. Our aim is to examine the safety and feasibility of antibiotic de-escalation in critically ill patients providing practical tips about how to accomplish this strategy in the critical care setting.