Open AccessReduced Levels of Serum FGF19 and Impaired Expression of Receptors for Endocrine FGFs in Adipose Tissue From HIV-Infected Patients
Author(s) -
José M. GallegoEscuredo,
Peré Domingo,
Maria del Mar Gutiérrez,
María Mateo,
M. Carmen Cabeza,
Àngels Fontanet,
Francesc Vidal,
Joan Carles Domingo,
Marta Giralt,
Francesc Villarroya
Publication year - 2012
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e318271c2c7
Subject(s) - lipodystrophy , fgf21 , fgf19 , adipose tissue , endocrinology , medicine , fibroblast growth factor , biology , insulin resistance , receptor , insulin , immunology , human immunodeficiency virus (hiv) , viral load , antiretroviral therapy
To determine the role of fibroblast growth factor (FGF)-19 and FGF21 and the endocrine FGFs receptor system in the metabolic alterations that manifest in HIV-1-infected patients undergoing highly active antiretroviral treatment (HAART).