Open AccessCD8+ T cells and Risk for Bacterial Pneumonia and All-Cause Mortality Among HIV-Infected Women
Author(s) -
Shruti K Gohil,
Moonseong Heo,
Ellie E. Schoenbaum,
David D. Celentano,
Liise Anne Pirofski
Publication year - 2012
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e31824d90fe
Subject(s) - hazard ratio , pneumonia , confidence interval , medicine , proportional hazards model , immunology , survival analysis , viral load , cd8 , human immunodeficiency virus (hiv) , immune system
Bacterial pneumonia risk is disproportionately high among those infected with HIV. This risk is present across all CD4(+) T-cell levels (TCLs), suggesting that additional factors govern susceptibility. This study examines CD8(+) TCLs and risk for HIV-associated bacterial pneumonia and all-cause mortality.