Open AccessHIV Replication Capacity Is an Independent Predictor of Disease Progression in Persons With Untreated Chronic HIV Infection
Author(s) -
Matthew Bidwell Goetz,
Robert Leduc,
Nicole Wyman,
Jay R. Kostman,
Ann M. Labriola,
Yolanda Lie,
Jodi Weidler,
Eoin Coakley,
Michael Bates,
Roberta Luskin-Hawk
Publication year - 2010
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0b013e3181cae480
Subject(s) - hazard ratio , viral load , medicine , cohort , gastroenterology , proportional hazards model , immunology , clinical endpoint , human immunodeficiency virus (hiv) , confidence interval , randomized controlled trial
To assess the effect of pol replication capacity (RC) on the hazard ratio of progression to a composite endpoint of time to progression to <350 CD4+ cells per microliter, initiation of therapy, or death.