Evolution of Integrase Resistance During Failure of Integrase Inhibitor-Based Antiretroviral Therapy | Zendy

Hiroyu Hatano | Zendy; Harry Lampiris | Zendy; Signe Fransen | Zendy; Soumi Gupta | Zendy; Wei Huang | Zendy; Rebecca Hoh | Zendy; Jeffrey N. Martin | Zendy; Jacob Lalezari | Zendy; David R. Bangsberg | Zendy; Christos J. Petropoulos | Zendy; Steven G. Deeks | Zendy

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Evolution of Integrase Resistance During Failure of Integrase Inhibitor-Based Antiretroviral Therapy

Author(s) -

Hiroyu Hatano,

Harry Lampiris,

Signe Fransen,

Soumi Gupta,

Wei Huang,

Rebecca Hoh,

Jeffrey N. Martin,

Jacob Lalezari,

David R. Bangsberg,

Christos J. Petropoulos,

Steven G. Deeks

Publication year - 2010

Publication title -

jaids journal of acquired immune deficiency syndromes

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.162

H-Index - 157

eISSN - 1944-7884

pISSN - 1525-4135

DOI - 10.1097/qai.0b013e3181c42ea4

Subject(s) - elvitegravir , raltegravir , integrase , integrase inhibitor , virology , biology , drug resistance , viral load , regimen , pharmacology , medicine , genetics , virus , human immunodeficiency virus (hiv) , antiretroviral therapy

Although integrase inhibitors are highly effective in the management of drug-resistant HIV, some patients fail to achieve durable viral suppression. The long-term consequences of integrase inhibitor failure have not been well defined.

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