Open AccessHIV-1 Recent Infection Testing Algorithm With Antiretroviral Drug Detection to Improve Accuracy of Incidence Estimates
Author(s) -
Andrew C. Voetsch,
Yen T. Duong,
Paul Stupp,
Suzue Saito,
Stephen McCracken,
Trudy Dobbs,
Frieda S. Winterhalter,
Daniel B. Williams,
Assegid Mengistu,
Owen Mugurungi,
Prisca Chikwanda,
Godfrey Musuka,
Clement B. Ndongmo,
Sindisiwe Dlamini,
Harriet NuwagabaBiribonwoha,
Munyaradzi Pasipamire,
Belete Tegbaru,
Frehywot Eshetu,
Samuel Biraro,
Jennifer Ward,
Dorothy Aibo,
Andrew Kabala,
George Mgomella,
Optatus Malewo,
Jeremiah Mushi,
Danielle Payne,
Yohannes Mengistu,
Fred Asiimwe,
Judith Shang,
E. Kainne Dokubo,
Laura T. Eno,
Anne-Cécile Zoung-Kanyi Bissek,
Leonard Kingwara,
Muthoni Junghae,
John Kiiru,
Richard C N Mwesigwa,
Shirish Balachandra,
Roger Lobog,
Elizabeth Kampira,
Mervi Detorio,
Ernest L. Yufenyuy,
Kristin Brown,
Hetal Patel,
Bharat Parekh
Publication year - 2021
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000002707
Subject(s) - incidence (geometry) , medicine , viral load , human immunodeficiency virus (hiv) , drug resistance , algorithm , immunoassay , antiretroviral therapy , immunology , avidity , virology , antigen , antibody , biology , mathematics , geometry , microbiology and biotechnology
HIV-1 incidence calculation currently includes recency classification by HIV-1 incidence assay and unsuppressed viral load (VL ≥ 1000 copies/mL) in a recent infection testing algorithm (RITA). However, persons with recent classification not virally suppressed and taking antiretroviral (ARV) medication may be misclassified.