Open AccessBeyond T Staging in the “Treat-All” Era: Severity and Heterogeneity of Kaposi Sarcoma in East Africa
Author(s) -
Esther E. Freeman,
Aggrey Semeere,
Devon E. McMahon,
Helen Byakwaga,
Miriam LakerOketta,
Susan Regan,
Megan Wenger,
Charles Kasozi,
Matthew Ssemakadde,
Mwebesa Bosco Bwana,
Michael Kanyesigye,
Philippa Kadama-Makanga,
Elyne Rotich,
Job Kisuya,
Kara WoolsKaloustian,
Ingrid V. Bassett,
Naftali Busakhala,
Jeffrey N. Martin
Publication year - 2021
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000002699
Subject(s) - medicine , sarcoma , stage (stratigraphy) , disease , clinical trial , surgery , pediatrics , pathology , paleontology , biology
Although many patients with Kaposi sarcoma (KS) in sub-Saharan Africa are diagnosed with AIDS Clinical Trials Group (ACTG) T1 disease, T1 staging insufficiently captures clinical heterogeneity of advanced KS. Using a representative community-based sample, we detailed disease severity at diagnosis to inform KS staging and treatment in sub-Saharan Africa.