Open AccessTrajectories of Depressive Symptoms, Neurocognitive Function, and Viral Suppression With Antiretroviral Therapy Among Youth With HIV Over 36 months
Author(s) -
Jaden R. Kohn,
Matthew Shane Loop,
Julie J. Kim-Chang,
Patricia A. Garvie,
John W. Sleasman,
Bernard M. Fischer,
H. Jonathon Rendina,
Steven Paul Woods,
Sharon L. Nichols,
Suzi Hong
Publication year - 2021
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000002653
Subject(s) - neurocognitive , depression (economics) , odds ratio , major depressive disorder , beck depression inventory , medicine , verbal learning , longitudinal study , psychomotor learning , psychiatry , psychology , cognition , clinical psychology , anxiety , pathology , economics , macroeconomics
Depression and neurocognitive impairment are highly prevalent among persons living with HIV and associated with poorer clinical outcomes; however, longitudinal studies of depression-neurocognition relationships in youth living with HIV (YLWH), and the role of antiretroviral therapy (ART), are lacking. This study tested whether (1) depressive symptomatology, across somatic, cognitive, and affective symptom domains, improved with ART and (2) more severe depressive symptoms at baseline were associated with poorer neurocognitive function and poorer HIV suppression.