Open AccessAcute HIV at the Time of Initiation of Pre-exposure or Post-exposure Prophylaxis: Impact on Drug Resistance and Clinical Outcomes
Author(s) -
Kent C. Johnson,
Miao-Jung Chen,
Robert Kohn,
Darpun Sachdev,
Oliver Bacon,
Sulggi A. Lee,
Stéphanie Cohen
Publication year - 2021
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000002638
Subject(s) - medicine , pre exposure prophylaxis , drug resistance , genotyping , hiv drug resistance , men who have sex with men , human immunodeficiency virus (hiv) , viral load , immunology , antiretroviral therapy , genotype , biochemistry , chemistry , syphilis , gene , microbiology and biotechnology , biology
Initiating pre-exposure or post-exposure prophylaxis (PrEP/PEP) in the setting of undiagnosed acute HIV (AHI) could cause antiretroviral resistance. We sought to characterize clinical outcomes and drug resistance mutations among individuals prescribed PrEP/PEP with undiagnosed AHI at a San Francisco sexually transmitted disease clinic.