Open AccessBrief Report: Bacterial Vaginosis and Risk of HIV Infection in the Context of CD101 Gene Variation
Author(s) -
Valentine Wanga,
Romel D. Mackelprang,
Katherine K. Thomas,
Deborah Donnell,
Craig R. Cohen,
Nelly Mugo,
Elizabeth A. Bukusi,
Guy de Bruyn,
Elizabeth Irungu,
Connie Celum,
Jared M. Baeten,
Jairam R. Lingappa,
Partners in Prevention Hsv,
Hiv Transmission Study
Publication year - 2020
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000002505
Subject(s) - bacterial vaginosis , medicine , context (archaeology) , immunology , hazard ratio , human immunodeficiency virus (hiv) , confidence interval , cohort , obstetrics , biology , paleontology
Whether bacterial vaginosis (BV) and CD101 immunoglobulin-like (Ig-like) variants independently increase HIV risk through mucosal inflammation is not well understood. We evaluated whether the impact of BV on HIV acquisition in women differs by the presence or absence of candidate CD101 Ig-like variants.