Open AccessBrief Report: Adiponectin Levels Linked to Subclinical Myocardial Fibrosis in HIV
Author(s) -
Julia B Balmaceda,
Khaled Z. AbdElmoniem,
Chia Ying Liu,
Julia Purdy,
Ronald Ouwerkerk,
Jatin R. Matta,
Jessica K Schenck,
Ahmed M. Gharib,
Colleen Hadigan
Publication year - 2020
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - Slovenian
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000002440
Subject(s) - adiponectin , medicine , myocardial fibrosis , adipokine , fibrosis , subclinical infection , cardiology , adipose tissue , body mass index , diabetes mellitus , endocrinology , insulin resistance , obesity
Persons living with HIV (PLWH) are at an increased risk of myocardial dysfunction and metabolic disturbances represent one of several potential contributing factors. Adiponectin is an adipokine that enhances insulin sensitivity with potential cardioprotective effects. We therefore investigated the relationship between myocardial fibrosis, adiponectin, and related metabolic parameters to better understand the pathophysiologic mechanisms of myocardial injury in PLWH.