Open AccessCumulative Burden of Depression and Neurocognitive Decline Among Persons With HIV: A Longitudinal Study
Author(s) -
Emily W Paolillo,
Elizabeth Pasipanodya,
Raeanne C. Moore,
Brian W. Pence,
J. Hampton Atkinson,
David J. Grelotti,
Igor Grant,
Robert K. Heaton,
David J. Moore
Publication year - 2020
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000002346
Subject(s) - neurocognitive , depression (economics) , medicine , beck depression inventory , longitudinal study , psychiatry , psychology , clinical psychology , cognition , anxiety , pathology , economics , macroeconomics
Higher cumulative burden of depression among people with HIV (PWH) is associated with poorer health outcomes; however, longitudinal relationships with neurocognition are unclear. This study examined hypotheses that among PWH, (1) higher cumulative burden of depression would relate to steeper declines in neurocognition, and (2) visit-to-visit depression severity would relate to fluctuations in neurocognition within persons.