Open AccessDeficits in Bone Architecture and Strength in Children Living With HIV on Antiretroviral Therapy
Author(s) -
Stephanie Shiau,
Michael T. Yin,
Renate Strehlau,
Megan Burke,
Faeezah Patel,
Louise Kuhn,
Ashraf Coovadia,
Shane A. Norris,
Stephen M. Arpadi,
Changes Bone Study Team
Publication year - 2020
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000002309
Subject(s) - quantitative computed tomography , bone mineral , medicine , regimen , ritonavir , efavirenz , osteoporosis , cortical bone , bone density , femoral neck , osteopenia , abacavir , surgery , nuclear medicine , viral load , antiretroviral therapy , human immunodeficiency virus (hiv) , anatomy , family medicine
Reduced bone mineral mass by dual x-ray absorptiometry is reported in children living with HIV (CLWH), but few studies of bone microarchitecture, particularly in sub-Saharan Africa, have been conducted. Here, we compare bone architecture and strength in black South African CLWH and uninfected control children by peripheral quantitative computed tomography (pQCT).