Open AccessNegative Diagnostic PCR Tests in School-Aged, HIV-Infected Children on Antiretroviral Therapy Since Early Life in Johannesburg, South Africa
Author(s) -
Faeezah Patel,
Cara Thurman,
Afaaf Liberty,
Megan Burke,
Renate Strehlau,
Stephanie Shiau,
Ashraf Coovadia,
Elaine J. Abrams,
Avy Violari,
Louise Kuhn
Publication year - 2020
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000002265
Subject(s) - medicine , confidence interval , efavirenz , viral load , antiretroviral therapy , cohort , pediatrics , cohort study , human immunodeficiency virus (hiv) , immunology
Younger age at antiretroviral therapy (ART) initiation has been associated with smaller HIV reservoirs. We investigated whether younger age of ART initiation is associated with testing negative and weaker signal on a standard HIV diagnostic test in treated children.