Open AccessBrief Report: Adipogenic Expression of Brown Fat Genes in HIV and HIV-Related Parameters
Author(s) -
Suman Srinivasa,
Martin Torriani,
Kathleen V. Fitch,
Patrick Maehler,
Sanjna Iyengar,
Meghan N. Feldpausch,
Aaron M. Cypess,
Steven Grinspoon
Publication year - 2019
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000002180
Subject(s) - adipose tissue , prdm16 , lipodystrophy , endocrinology , medicine , context (archaeology) , viral load , adipogenesis , biology , immunology , brown adipose tissue , human immunodeficiency virus (hiv) , antiretroviral therapy , paleontology
Persons with HIV are at increased risk for adipose dysfunction, which could mediate metabolic complications such as cardiovascular disease, fatty liver disease, and diabetes. We have previously reported reduced browning and beiging capacity of the subcutaneous adipose depot in HIV.