Open AccessBrief Report: No Evidence for an Association Between Statin Use and Lower Biomarkers of HIV Persistence or Immune Activation/Inflammation During Effective ART
Author(s) -
Roger Bedimo,
Hanna Mar,
Ronald J. Bosch,
Henning Drechsler,
Joshua C. Cyktor,
Bernard Macatangay,
Christina M. Lalama,
Charles R. Rinaldo,
Ann C. Collier,
Catherine Godfrey,
Evelyn Hogg,
Christopher Hensel,
Joseph J. Eron,
Deborah McMahon,
John W. Mellors,
Pablo Tebas,
Rajesh T. Gandhi,
A Study Team
Publication year - 2019
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000002124
Subject(s) - immune system , inflammation , statin , persistence (discontinuity) , medicine , immunology , rna , neopterin , biology , genetics , gene , geotechnical engineering , engineering
Statins exert pleiotropic anti-inflammatory and immune-modulatory effects, which might translate into antiviral activity. We evaluated whether reported current statin exposure is associated with lower levels of markers of HIV persistence and immune activation/inflammation.