Open AccessTreatment Adherence Among Persons Receiving Concurrent Multidrug-Resistant Tuberculosis and HIV Treatment in KwaZulu-Natal, South Africa
Author(s) -
Fay K Stephens,
Neel R. Gandhi,
James C.M. Brust,
Koleka Mlisana,
Prashini Moodley,
Salim Allana,
Angie Campbell,
Sarita Shah
Publication year - 2019
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000002120
Subject(s) - medicine , tuberculosis , directly observed therapy , pill , adverse effect , medication adherence , tb treatment , pediatrics , pathology , pharmacology
Success in multidrug-resistant tuberculosis (MDR-TB) and HIV treatment requires high medication adherence despite high pill burdens, frequent adverse events, and long treatment duration, which may jeopardize adherence. We prospectively compared MDR-TB/HIV-coinfected persons to those with MDR-TB alone to determine the impact of concurrent treatment on adherence and outcomes.