Open AccessEffect of Lactobacillus rhamnosus GG Supplementation on Intestinal Inflammation Assessed by PET/MRI Scans and Gut Microbiota Composition in HIV-Infected Individuals
Author(s) -
Caroline J. Arnbjerg,
Beate Vestad,
Johannes R. Hov,
Kim Steenstrup Pedersen,
Sofie Jespersen,
Helle Hjorth Johannesen,
Kristian Holm,
Bente Halvorsen,
Eva Fallentin,
Adam E. Hansen,
Theis Lange,
Andreas Kjær,
Marius Trøseid,
Barbara Fischer,
Susanne Dam Nielsen
Publication year - 2018
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000001693
Subject(s) - lactobacillus rhamnosus , inflammation , gut flora , lactobacillus , microbiome , cart , systemic inflammation , gastroenterology , probiotic , medicine , immunology , biology , bacteria , bioinformatics , genetics , engineering , mechanical engineering
Alterations in the gut microbiome have been associated with inflammation and increased cardiovascular risk in HIV-infected individuals. The aim of this study was to investigate the effects of the probiotic strain Lactobacillus rhamnosus GG (LGG) on intestinal inflammation, gut microbiota composition, and systemic markers of microbial translocation and inflammation in HIV-infected individuals.