Open AccessBrief Report: Tenofovir-Associated Nephrotoxicity Among a US National Historical Cohort of HIV-Infected Veterans: Risk Modification by Concomitant Antiretrovirals
Author(s) -
Joanne LaFleur,
Adam P. Bress,
Stephen Esker,
Kristin Knippenberg,
Jacob Crook,
Heather Nyman,
Roger Bedimo,
Pablo Tebas,
Lisa Rosenblatt
Publication year - 2018
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000001608
Subject(s) - tenofovir , concomitant , medicine , human immunodeficiency virus (hiv) , nephrotoxicity , cohort , cohort study , virology , antiretroviral therapy , viral load , kidney
Tenofovir disoproxil fumarate (TDF) has been associated with renal complications. The third agent in TDF-containing antiretroviral regimens may modify that risk. We compared renal adverse outcomes among treatment-naive HIV-infected patients initiating TDF-containing regimens including efavirenz (EFV) or other agents.