Open AccessPre-Exposure Prophylaxis (PrEP) Use and Condomless Anal Sex: Evidence of Risk Compensation in a Cohort of Young Men Who Have Sex with Men
Author(s) -
Michael E. Newcomb,
Kevin Moran,
Brian A. Feinstein,
Emily C. Forscher,
Brian Mustanski
Publication year - 2018
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.162
H-Index - 157
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000001604
Subject(s) - pre exposure prophylaxis , men who have sex with men , anal sex , risk compensation , cohort , homosexuality , medicine , human immunodeficiency virus (hiv) , demography , young adult , cohort study , family medicine , psychology , gerontology , syphilis , sociology , psychoanalysis
Young men who have sex with men (YMSM) are disproportionately impacted by HIV. Pre-exposure prophylaxis (PrEP) is highly effective at preventing HIV acquisition. It remains unclear if PrEP use increases rates of condomless sex (ie, risk compensation), which may increase risk of infection if PrEP adherence is not optimal. This study aimed to examine whether PrEP use and PrEP adherence were associated with change in sexual risk behaviors in a large longitudinal cohort of YMSM reporting on multiple sexual partnerships over time.