Open AccessHIV-1 Shedding From the Female Genital Tract is Associated With Increased Th1 Cytokines/Chemokines That Maintain Tissue Homeostasis and Proportions of CD8+FOXP3+ T Cells
Author(s) -
Marta E. Bull,
Jillian Legard,
Kenneth Tapia,
Bess Sorensen,
Susan E. Cohn,
Rochelle Garcia,
Sarah Holte,
Robert W. Coombs,
Jane Hitti
Publication year - 2014
Publication title -
journal of acquired immune deficiency syndromes
Language(s) - English
Resource type - Journals
eISSN - 1944-7884
pISSN - 1525-4135
DOI - 10.1097/qai.0000000000000336
Subject(s) - chemokine , viral shedding , immunology , foxp3 , biology , immune system , cd8 , cytokine , t cell , inflammation , antibody
HIV-1 shedding from the female genital tract is associated with increased sexual and perinatal transmission and has been broadly evaluated in cross-sectional studies. However, few longitudinal studies have evaluated how the immune microenvironment effects shedding.