Vitamin D attenuates nucleoside reverse transcriptase inhibitor induced human skeletal muscle mitochondria DNA depletion | Zendy

Grant R. Campbell | Zendy; Zachary T. Pallack | Zendy; Stephen A. Spector | Zendy

Open Access

Vitamin D attenuates nucleoside reverse transcriptase inhibitor induced human skeletal muscle mitochondria DNA depletion

Author(s) -

Grant R. Campbell,

Zachary T. Pallack,

Stephen A. Spector

Publication year - 2013

Publication title -

aids

Language(s) - Uncategorized

Resource type - Journals

SCImago Journal Rank - 2.195

H-Index - 216

eISSN - 1473-5571

pISSN - 0269-9370

DOI - 10.1097/qad.0b013e32836010dd

Subject(s) - reverse transcriptase , nucleoside reverse transcriptase inhibitor , reverse transcriptase inhibitor , skeletal muscle , nucleoside , mitochondrion , mitochondrial dna , dna , chemistry , biology , endocrinology , biochemistry , rna , gene

To evaluate the impact of the active metabolite of vitamin D, 1α,25-dihydroxycholecalciferol (1,25D3), on nucleoside reverse transcriptase inhibitor (NRTI) induced mitochondrial DNA (mtDNA) depletion in human skeletal muscle myoblasts and myotubes.

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