Open AccessLong-term nonprogressors and elite controllers in the ANRS CO5 HIV-2 cohort
Author(s) -
Rodolphe Thiébaut,
Sophie Matheron,
Audrey Taïeb,
Françoise BrunVézinet,
Geneviève Chêne,
Brigitte Autran
Publication year - 2011
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e328344892e
Subject(s) - asymptomatic , cohort , human immunodeficiency virus (hiv) , confidence interval , medicine , sida , cohort study , immunology , multicenter aids cohort study , viral disease , virology , demography , sociology
Among 342 HIV-2-infected patients of the ANRS CO5 HIV-2 cohort, the prevalence of long-term nonprogressors (LTNPs) (i.e. asymptomatic for at least 8 years while maintaining CD4 cell count at least 500 cells/μl) and of HIV controllers (i.e. controlling HIV replication in the absence of antiretroviral treatment for at least 10 years) was 6.1% (95% confidence interval 3.9-9.1) and 9.1% (6.3-12.7), respectively. Most LTNPs (81%) were HIV controllers, whereas only 55% of HIV controllers were LTNPs.