Long-term nonprogressors and elite controllers in the ANRS CO5 HIV-2 cohort | Zendy

Rodolphe Thiébaut | Zendy; Sophie Matheron | Zendy; Audrey Taïeb | Zendy; Françoise BrunVézinet | Zendy; Geneviève Chêne | Zendy; Brigitte Autran | Zendy

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Long-term nonprogressors and elite controllers in the ANRS CO5 HIV-2 cohort

Author(s) -

Rodolphe Thiébaut,

Sophie Matheron,

Audrey Taïeb,

Françoise BrunVézinet,

Geneviève Chêne,

Brigitte Autran

Publication year - 2011

Publication title -

aids

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.195

H-Index - 216

eISSN - 1473-5571

pISSN - 0269-9370

DOI - 10.1097/qad.0b013e328344892e

Subject(s) - asymptomatic , cohort , human immunodeficiency virus (hiv) , confidence interval , medicine , sida , cohort study , immunology , multicenter aids cohort study , viral disease , virology , demography , sociology

Among 342 HIV-2-infected patients of the ANRS CO5 HIV-2 cohort, the prevalence of long-term nonprogressors (LTNPs) (i.e. asymptomatic for at least 8 years while maintaining CD4 cell count at least 500 cells/μl) and of HIV controllers (i.e. controlling HIV replication in the absence of antiretroviral treatment for at least 10 years) was 6.1% (95% confidence interval 3.9-9.1) and 9.1% (6.3-12.7), respectively. Most LTNPs (81%) were HIV controllers, whereas only 55% of HIV controllers were LTNPs.

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