Open AccessImpact of HAART and CNS-penetrating antiretroviral regimens on HIV encephalopathy among perinatally infected children and adolescents
Author(s) -
Kunjal Patel,
Xue Ming,
Paige L. Williams,
Kevin Robertson,
James M. Oleske,
George R. Seage
Publication year - 2009
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e32832dc041
Subject(s) - encephalopathy , medicine , incidence (geometry) , pediatrics , prospective cohort study , cohort study , cohort , cumulative incidence , confidence interval , physics , optics
Prior to antiretroviral treatment, HIV-infected children frequently developed encephalopathy, resulting in debilitating morbidity and mortality. This is the first large study to evaluate the impact of HAART and central nervous system (CNS)-penetrating antiretroviral regimens on the incidence of HIV encephalopathy and survival after diagnosis of HIV encephalopathy among perinatally infected children.