Open AccessCurrent V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates
Author(s) -
Andrew Low,
Winnie Dong,
Dennison Chan,
Tobias Sing,
Ronald Swanstrom,
Mark A. Jensen,
Satish K. Pillai,
Benjamin M. Good,
P. Richard Harrigan
Publication year - 2007
Publication title -
aids
Language(s) - Uncategorized
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0b013e3282ef81ea
Subject(s) - tropism , co receptor , genotyping , algorithm , phenotype , v3 loop , computational biology , receptor , biology , medicine , genotype , virology , mathematics , genetics , virus , gene , peptide sequence
Integrating CCR5 antagonists into clinical practice would benefit from accurate assays of co-receptor usage (CCR5 versus CXCR4) with fast turnaround and low cost.