Open AccessSARS-CoV-2 incidence, testing rates, and severe COVID-19 outcomes among people with and without HIV
Author(s) -
Matthew A Spinelli,
Lillian B. Brown,
David V. Glidden,
Kyle Hunter,
Patrick Martin-Tuite,
James Zheng,
Curtis Sera,
Diane V. Havlir,
Susan Buchbinder,
Monica Gandhi
Publication year - 2021
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000003075
Subject(s) - medicine , covid-19 , confidence interval , incidence (geometry) , vaccination , emergency medicine , relative risk , disease , immunology , virology , outbreak , infectious disease (medical specialty) , physics , optics
To assess SARS-CoV-2 outcomes, we matched a municipal COVID-19 registry and clinic rosters from a municipal primary care network containing a large HIV clinic and assessed clinical outcomes by HIV status. The risk of severe COVID-19 was higher among people with HIV (PWH, adjusted relative risk = 1.84, 95% confidence interval = 1.05-3.25), while SARS-CoV-2 incidence was lower despite higher testing rates. SARS-CoV-2 vaccination campaigns should prioritize PWH to prevent severe COVID-19 disease given potentially higher risk.