Open AccessPatterns of pretreatment drug resistance mutations of very early diagnosed and treated infants in Botswana
Author(s) -
Natasha O. Moraka,
Pilar García-Broncano,
Zixin Hu,
Gbolahan Ajibola,
Ontlametse T. Bareng,
Molly Pretorius-Holme,
Kenneth Maswabi,
Comfort Maphorisa,
Terence Mohammed,
Simani Gaseitsiwe,
Gert U VanZyl,
Daniel R. Kuritzkes,
Mathias Lichterfeld,
Sikhulile Moyo,
Roger Shapiro
Publication year - 2021
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000003041
Subject(s) - sanger sequencing , peripheral blood mononuclear cell , drug resistance , virology , medicine , protease , viral load , mutation , drug , protease inhibitor (pharmacology) , human immunodeficiency virus (hiv) , antiretroviral drug , immunology , dna sequencing , antiretroviral therapy , pharmacology , biology , dna , in vitro , enzyme , genetics , gene , biochemistry
To describe the occurrence of HIV drug resistance mutations (DRMs) in both intact and defective HIV-1 cell-associated DNA (HIV-1 CAD) among early-treated infants.