Open AccessPrevalent human papillomavirus infection increases the risk of HIV acquisition in African women: advancing the argument for human papillomavirus immunization
Author(s) -
Liu Gui,
Nelly Mugo,
Elizabeth R. Brown,
Nyaradzo Mgodi,
Z.M. Chirenje,
Jeanne Marrazzo,
Rachel L. Winer,
Leila E. Mansoor,
Thesla PalaneePhillips,
Samantha Siva,
Logashvari Naidoo,
Nitesha Jeenarain,
Zakir Gaffoor,
Gonasagrie Nair,
Pearl Selepe,
Clemensia Nakabiito,
Baningi Mkhize,
Brenda Gati Mirembe,
Marthinette Taljaard,
Ravindre Panchia,
Jared M. Baeten,
Jennifer E. Balkus,
Florian Hladik,
Connie Celum,
Ruanne V. Barnabas
Publication year - 2021
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000003004
Subject(s) - medicine , odds ratio , seroconversion , confidence interval , hpv infection , chemoprophylaxis , case control study , logistic regression , immunology , cervical cancer , obstetrics , human immunodeficiency virus (hiv) , cancer
Vaccine-preventable human papillomavirus (HPV) infection is common, especially in sub-Saharan Africa where HIV risk is also high. However, unlike other sexually transmitted infections (STIs), HPV's role in HIV acquisition is unclear. We evaluated this relationship using data from MTN-003, a clinical trial of HIV chemoprophylaxis among cisgender women in sub-Saharan Africa.