Open AccessTesamorelin improves fat quality independent of changes in fat quantity
Author(s) -
Jordan E. Lake,
Kristen La,
Kristine M. Erlandson,
Stefan Adrian,
Gayane Yenokyan,
Ann Scherzinger,
Michael P. Dubé,
Takara Stanley,
Steven Grinspoon,
Julian Falutz,
Jean-Claude Mamputu,
Christian Marsolais,
Grace A. McComsey,
Todd T. Brown
Publication year - 2021
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002897
Subject(s) - placebo , medicine , confidence interval , hounsfield scale , subcutaneous fat , endocrinology , zoology , gastroenterology , adipose tissue , surgery , computed tomography , biology , pathology , alternative medicine
Fat quality and quantity may affect health similarly or differently. Fat quality can be assessed by measuring fat density on CT scan (greater density = smaller, higher quality adipocytes). We assessed the effects of tesamorelin, a growth hormone-releasing hormone analogue that reduces visceral fat (VAT) quantity in some people living with HIV (PWH), on fat density.