Open AccessMitochondrial DNA haplogroups and weight gain following switch to integrase strand transfer inhibitor-based antiretroviral therapy
Author(s) -
Kristine M. Erlandson,
Kun Wu,
Jordan E. Lake,
David C. Samuels,
Sara H Bares,
Katherine Tassiopoulos,
John R. Koethe,
Todd T. Brown,
Michael Leonard,
Constance A. Benson,
David W. Haas,
Todd Hulgan
Publication year - 2020
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002771
Subject(s) - haplogroup , human mitochondrial dna haplogroup , mitochondrial dna , genotyping , genetics , medicine , demography , haplotype , biology , genotype , gene , sociology
Integrase strand transfer inhibitor (INSTI)-based antiretroviral therapy (ART) has been associated with excess weight gain in some adults, which may be influenced by genetic factors. We assessed mitochondrial DNA (mtDNA) haplogroups and weight gain following switch to INSTI-based ART.