Open AccessInfluence of dapivirine vaginal ring use on cervicovaginal immunity and functional microbiome in adolescent girls
Author(s) -
Christina Farr Zuend,
Laura NoëlRomas,
Sarah Hoger,
Stuart McCorriser,
Garrett Westmacott,
Jeanne Marrazzo,
Sharon L. Hillier,
Charlene S. Dezzutti,
Kathleen Squires,
Katherine Bunge,
Adam Burgener
Publication year - 2020
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002751
Subject(s) - lactobacillus crispatus , vaginal ring , microbiome , lactobacillus , prevotella , placebo , medicine , biology , physiology , immunology , microbiology and biotechnology , population , bioinformatics , bacteria , pathology , genetics , alternative medicine , environmental health , family planning , research methodology
The antiretroviral-based dapivirine vaginal ring reduced HIV risk among women in phase III clinical trials. However, limited data exists on the impact of dapivirine on the vaginal microenvironment in adolescents.