Open AccessSubstantial decline in heavily treated therapy-experienced persons with HIV with limited antiretroviral treatment options
Author(s) -
Kristina L. Bajema,
Robin M. Nance,
Joseph A. Delaney,
Ellen Eaton,
Thibaut Davy-Méndez,
Maile Y. Karris,
Richard D. Moore,
Joseph J. Eron,
Benigno Rodrı́guez,
Kenneth H. Mayer,
Elvin Geng,
Cindy Garris,
Michael S. Saag,
Heidi M. Crane,
Mari M. Kitahata
Publication year - 2020
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002679
Subject(s) - medicine , hazard ratio , antiretroviral therapy , confidence interval , proportional hazards model , cohort , cohort study , human immunodeficiency virus (hiv) , young adult , multicenter aids cohort study , demography , viral load , immunology , sociology
Historically, a high burden of resistance to antiretroviral therapy (ART) in heavily treatment-experienced (HTE) persons with HIV (PWH) resulted in limited treatment options (LTOs). We evaluated the prevalence, risk factors, and virologic control of HTE PWH with LTO throughout the modern ART era.