Open AccessHIV infection and COVID-19: risk factors for severe disease
Author(s) -
Nicolas Etienne,
Marina Karmochkine,
Laurence Slama,
Juliette Pavie,
Dominique Batisse,
Rafael Usubillaga,
V. Letembet,
Patricia Brazille,
Etienne Canouï,
Dorsaf Slama,
Hassan Joumaa,
Florence CanouïPoitrine,
Lauriane Segaux,
Laurence Weiss,
Jean Paul Viard,
Dominique Salmon
Publication year - 2020
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002651
Subject(s) - covid-19 , observational study , medicine , multivariate analysis , human immunodeficiency virus (hiv) , disease , risk factor , prospective cohort study , immunology , virology , outbreak , infectious disease (medical specialty)
: We performed an observational prospective monocentric study in patients living with HIV (PLWH) diagnosed with COVID-19. Fifty-four PLWH developed COVID-19 with 14 severe (25.9%) and five critical cases (9.3%), respectively. By multivariate analysis, age, male sex, ethnic origin from sub-Saharan Africa and metabolic disorder were associated with severe or critical forms of COVID-19. Prior CD4 T cell counts did not differ between groups. No protective effect of a particular antiretroviral class was observed.