Open AccessHigher frequencies of functional HIV-envelope-specific memory B cells are associated with nonprogressive HIV infection in Indian population
Author(s) -
Jayshree Dhande,
Kasturi Saikia,
Dharmendra Singh,
Rajani Bagul,
Smita Kulkarni,
Manisha Ghate,
Madhuri Thakar
Publication year - 2020
Publication title -
aids
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.195
H-Index - 216
eISSN - 1473-5571
pISSN - 0269-9370
DOI - 10.1097/qad.0000000000002620
Subject(s) - population , flow cytometry , cd38 , immunology , antibody , human immunodeficiency virus (hiv) , medicine , virology , biology , stem cell , microbiology and biotechnology , environmental health , cd34
The HIV-1-specific antibodies are being considered for prevention and therapy in HIV infection. For effective antibody response, presence of functionally competent memory B cells (MEBs) is important; however, HIV-infection is known to alter the B-cell functionality. Very limited data are available on the HIV-specific memory B-cell population in HIV-infected Indian population.